Introduction: Nonalcoholic fatty liver disease (NAFLD) is one of the most important causes of liver disease worldwide and will probably emerge as the leading cause of end-stage liver disease in the coming decades, with the disease affecting both adults and children. Objective: The present study had undertaken to study the Prevalence of Non-Alcoholic Fatty Liver Disease in Hypertensive Patients. Method: A Prospective observational study was conducted during October 2020 to October 2022 at Department of Medicine, Government Medical College and Hospital, Chh. Sambhajinagar, Maharashtra, India Patient with history of Hypertension and age more than 18 years were enrolled in this study. Results:  In present study, out of 600 cases screened only 350 cases of HTN came for follow-up and among them 90 patients were diagnosed as NAFLD. This prevalence of NAFLD among hypertensive patient was 25.71%. The Mean age of patients was found to be 42.70 ± 7.34 years. Maximum numbers of cases were females 52.22% and males 47.78%. Male to female ratio was 1.09:1. Most of patient 56.67% residing in rural area followed by 43.33% were from urban area. Majority of 56.0% patients were having NAFLD Grade II followed by 40.0% of grade I and 4% of grade III NAFLD. Conclusion: The prevalence of NAFLD among hypertensive patient was 25.71%. Most of patients had history of hypertension of 5-10 years. Majority of patients under study were obese and overweight BMI was found to be significantly associated NAFLD.  It can be inferred that a clinician should have a high index of suspicion in order to detect NAFLD early in the course of the disease as symptoms and signs of NAFLD are non-specific duration and occur later in the course of the disease. Early detection would help not only in modifying the disease course and delaying its complications but would also play a major role in preventive of disease.

DOI: 10.5281/zenodo.

Introduction: Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of clinic-pathologic entities that have in common the presence of fat accumulation in the liver in the absence of significant alcohol consumption. The epidemiology and demographic characteristics of NAFLD vary worldwide, usually parallel to the prevalence of obesity, but a substantial proportion of patients are lean. The present study is conducted to study the clinical profile of non-alcoholic fatty liver disease in hypertensive patients. Method: A Prospective observational study was conducted during October 2020 to October 2022 at Department of Medicine, Government Medical College and Hospital, Chh. Sambhajinagar, Maharashtra, India. Patient diagnosed NAFLD with hypertension and age more than 18 years were enrolled in this study. Results: In present study, 90 patients of NAFLD with HTN were enrolled. Most of the patients 46.67% had 2nd degree of NAFLD followed by 43.33% had 1st degree and 10% had 3rd degree of non-alcoholic fatty liver disease. There was statistical significance relation between diastolic BP and degree of NAFLD (p=0.035). No mortality was seen among study patients. In multivariate analysis non-alcoholic fatty liver disease grading was significantly related with BMI (p=0.0001), W/H ratio (p=0.0001) & triglyceride (p=0.004). Conclusion: There was statistical significance relation between diastolic BP and degree of NAFLD. In multivariate analysis non-alcoholic fatty liver disease grading was significantly related with BMI, W/H ratio & triglyceride. Early detection would help not only in modifying the disease course and delaying its complications but would also play a major role in preventive cardiology as its association with metabolic syndrome is frequent and its components are well documented cardiovascular risk factors.

DOI: 10.5281/zenodo.