1. AN RECENT ADVANCEMENT IN TOPICAL DOSAGE FORMS: A REVIEW Pooja Kumari, Dilip Agrawal, Ashok Kumar Sharma, Mohit Khandelwal, Shaneza Aman, Shweta bhandari
There are many semisolid dosage forms but creams, pastes, emulsions, ointments, gels, and rigid foams etc are main examples of this category of dosage form. They serve as carriers for drugs that are topically, administered by route of the skin (derma), retina, rectal tissue, nasal mucosa, vagina, buccal tissue, urethral membrane, and external ear lining. Extant definitions of lotions, gels, creams and ointments vary depending on literature source, market history or traditional use. This often leads to confusion when deciding which topical Dosages forms to prescribe and purchase. The purpose of this study is to obtain a scientifically based, regular classification of Dosages forms for topical drugs. A variety of prescriptions and over the counter topical products currently marketed as lotions, gels, creams, and ointments are evaluations using variant techniques including rheology, viscosity and shear rate versus shear stress, loss on drying , specific gravity, surface tension, thermogravimetric analysis (TGA), water absorption, dilution properties, microscopic evaluation, transmittance of visible light, features (appearance)or conformation (composition). Skin is the largest organ of the humanitarian corpus and plays the most important role in protecting against microorganisms and foreign body. The important instruments such as topical, regional and Transdermal are widely used for delivery of variant dosages forms. The main use of semi-solid dosage form additives are controlling the development of absorption, maintaining the viscosity, improving the stability as well as organoleptic (sense organs) Property and increasing the bulk of the (synthesis) formulation.