Volume5,Issue4,Article4

Anti-inflammatory Activity of Aerial Part of Maerua apetala Roth (Jacobs) Against Carrageenan Induced Paw Edema.
M.Packia Lincy, V.R.Mohan, S.Jeeva

The present study was conducted to evaluate the antiinflammatory activity in the ethanol extract of aerial part ofMaerua apetala. The antiinflammatory activity was assessed by carrageenan induced paw oedema in albino rats. The aerial part extract of this plant were administered orally at doses of 100, 150 and 300 mg / kg body weight and the study was compared with a standard drug indomethacin (10 mg / kg). The highest dose of Maerua apetala aerial part extracts (300 mg / kg) produced a maximum inhibition of 84.17% at 3 hours after administration which was more effective. Further detailed studies are in progress for the isolation of single entity responsible for antiinflammatory activity and development of suitable formulations.

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